Camptothecin  – anti-cancerous API

Camptothecin is an API which is used by the Pharma industry.

CAS Number: 7689-03-4
Molecular formula: C20H16N2O4

Camptothecin (CPT) is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I). CPT showed remarkable anticancer activity in preliminary clinical trials but also low solubility and adverse drug reaction. Because of these disadvantages, synthetic and medicinal chemists have developed numerous syntheses of Campto and various derivatives to increase the benefits of the chemical, with good results. Two CPT analogues have been approved and are used in cancer chemotherapy today, Topotecan and Irinotecan.

At Himachal Pharmaceuticals we manufacture CPT for bulk requirements as Active Pharmaceutical Ingredients for the Pharmaceutical or Drug manufacturing companies, agents or other industrial bulk consumers.