Rutin NF

Written by

Reviewed by

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Gaurav Sood

Partner - HimPharm

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Dr B M Sood

Chairman - HimPharm

Rutin Manufactured by HimPharm

Category: Flavonoid glycoside
Trade Names: Rutin, Rutin NF, rutoside, quercetin-3-rutinoside, sophorin
Routes of Administration: Oral ingestion, topical application
ATC Code: Not applicable


  • CAS Number: 153-18-4
  • PubChem CID: 5280805
  • ChemSpider ID: 4444939
  • IUPAC Name (2S,3R,4S,5R,6R)-2-[3,4-dihydroxy-5-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • DrugBank ID: DB02237
  • UNII: 9G1AX7470J
  • KEGG ID: C10883
  • ChEBI ID: 17829
  • ChEMBL ID: CHEMBL299966
  • CompTox Dashboard (EPA): DTXSID3022853
  • ECHA InfoCard: 100.012.907

Chemical and Physical Data

  • Molecular Formula C27H30O16
  • Molar Mass 610.52 g/mol

SMILES: C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O[C@@H]4C@@HO)O

InChI: InChI=1S/C27H30O16/c28-8-16-19(32)21(34)23(36)26(40-16)39-15-7-11(3-5-17(30)31)24(37)25(38)27(15,41-23)42-22-18(33)9-1-13(29)20(35-22)10-2-14(30)12(4-6-16)36-7/h1-6,8,15,16,18-26,28-38H,7,9-10H2/t15-,16-,18+,19+,20-,21+,22-,23+,24+,25+,26+,27-/m0/s1



Rutin, also known as rutoside, quercetin-3-rutinoside, or sophorin, stands as a prominent citrus flavonoid glycoside. Its molecular formula, C27H30O16, hints at its complex yet beneficial nature. Rutin possesses remarkable properties that have piqued the interest of the pharmaceutical, healthcare, and natural products industries.

This multifaceted compound inhibits platelet aggregation, thereby facilitating blood thinning and enhancing circulation. Rutin’s anti-inflammatory attributes, coupled with its ability to inhibit aldose reductase activity, render it a valuable asset in combating various health challenges. From strengthening capillaries to potentially reducing symptoms of haemophilia, Rutin unfolds a tapestry of health benefits.


Impact of Rutin on Pharmaceutical, Drug, and Natural Products Industry

Rutin’s impact reverberates across diverse sectors, shaping the landscape of pharmaceuticals, drugs, and natural products. Its versatility in addressing health concerns, coupled with its potential therapeutic applications, has sparked intrigue within these industries. 

Rutin’s presence offers a promising avenue for innovation, paving the way for novel formulations and treatments.

As researchers delve deeper into Rutin’s properties and mechanisms of action, its significance continues to burgeon. From post-thrombotic syndrome to venous insufficiency, Rutin holds promise in ameliorating ailments that afflict millions worldwide. 

HimPharm, with its steadfast commitment to quality and innovation, stands poised at the forefront of Rutin production, spearheading advancements that resonate far beyond conventional boundaries.

Understanding Rutin

What is Rutin?

Rutin emerges as a flavonoid glycoside, seamlessly intertwining the flavonol quercetin with the disaccharide rutinose. Found abundantly in various plant sources, including citrus, Rutin’s chemical composition underscores its therapeutic potential. Its intricate molecular structure underscores its diverse biological activities, making it a prized asset in the realm of natural medicine.

Rutin’s Uses

Rutin’s uses span a spectrum of health applications, owing to its diverse pharmacological properties. From its role in mitigating inflammation to its potential in cardiovascular health, Rutin’s versatility extends across multiple domains. As researchers unravel its mechanisms of action, Rutin’s therapeutic repertoire continues to expand, offering new avenues for exploration and discovery.

Physical Characteristics of Rutin

Rutin manifests in various physical forms, ranging from crystalline powders to amorphous solids. Its color may vary from pale yellow to yellowish-green, depending on factors such as purity and processing methods. Rutin’s solubility in water remains limited, presenting challenges in formulation and delivery. However, innovative techniques and formulations have circumvented these limitations, unlocking Rutin’s full therapeutic potential.

Extraction and Processing of Rutin

The extraction of Rutin involves meticulous processes aimed at isolating and purifying this valuable compound from plant sources. From citrus fruits to buckwheat, Rutin’s extraction sources vary, each presenting unique challenges and opportunities. HimPharm’s expertise in extraction and processing techniques ensures the integrity and purity of Rutin, setting the standard for quality and excellence.

Importance of Rutin

Rutin’s importance transcends conventional boundaries, encompassing realms of health and wellness previously untapped. Its role in improving circulation, reducing inflammation, and enhancing cardiovascular health underscores its significance in modern medicine. Rutin’s presence heralds a new era of natural therapeutics, offering hope and healing to millions worldwide.

Applications of Rutin

Rutin finds applications across a myriad of health conditions, ranging from cardiovascular disorders to inflammatory diseases. Its multifaceted properties render it a versatile asset in formulations targeting diverse health concerns. From dietary supplements to pharmaceutical formulations, Rutin’s applications continue to expand, driven by advances in scientific research and innovation.

History of Rutin

Rutin’s history is steeped in centuries of herbal tradition, dating back to ancient civilizations that revered its medicinal properties. From traditional remedies to modern pharmacology, Rutin’s journey reflects the evolution of medical science. HimPharm’s dedication to preserving this rich heritage underscores its commitment to excellence and innovation in Rutin production.

Exploring Rutin and its Use in Pharmaceuticals and Healthcare

Rutin’s Uses and Properties

Delving deeper into Rutin’s pharmacological profile, its uses span various therapeutic areas. Rutin’s antioxidant properties make it a formidable combatant against oxidative stress, a contributor to various chronic diseases. Its anti-inflammatory effects position it as a potential ally in addressing conditions marked by excessive inflammation.

Additional Properties of Rutin

Beyond its antioxidant and anti-inflammatory attributes, Rutin exhibits antithrombotic properties, contributing to cardiovascular health. Studies suggest its potential in improving venous tone, making it relevant in conditions like chronic venous insufficiency. The multifaceted nature of Rutin positions it as a compound of interest for researchers seeking holistic solutions in healthcare.

The Raw Material from which Rutin is Obtained

Raw Material Overview

Rutin’s primary source lies in the bountiful realm of nature. Plants, especially citrus fruits and buckwheat, serve as the raw material from which this valuable compound is extracted. HimPharm extracts Rutin from Sophora japonica, recognizing the importance of sourcing the finest raw materials, ensures a supply chain that upholds the integrity and quality of Rutin production.

Alternative Sources of Raw Material for Rutin Extraction

While citrus fruits and buckwheat remain primary sources, ongoing research explores alternative botanical reservoirs for Rutin. This not only diversifies the supply chain but also contributes to sustainable practices in the pharmaceutical and natural products industries. HimPharm remains at the forefront, continuously evaluating and incorporating advancements in raw material sourcing.

HimPharm Manufacturing Standards

HimPharm’s Role in Rutin Production

HimPharm’s commitment to Rutin production is marked by a fusion of tradition and innovation. With state-of-the-art facilities and adherence to rigorous quality standards, HimPharm plays a pivotal role in meeting the escalating demand for Rutin in the global market. The company’s dedication to excellence extends from sourcing raw materials to delivering the final product.

Upholding International Quality Standards

In the realm of pharmaceuticals and natural products, quality is non-negotiable. HimPharm’s manufacturing standards align with international benchmarks, ensuring that Rutin produced meets or exceeds stringent quality criteria. The company’s quality assurance protocols encompass every stage of production, instilling confidence in partners and consumers alike.

HimPharm’s Commitment to Fulfilling Bulk Rutin Requirements

The growing demand for Rutin necessitates a robust supply chain. HimPharm, cognizant of this demand, positions itself as a reliable partner for bulk Rutin requirements. Whether for pharmaceutical formulations or natural product innovations, HimPharm’s capacity to meet bulk orders underscores its commitment to supporting the industry’s evolving needs.

Rutin Production Processes

Details of the Step-by-Step Manufacturing Process of Rutin

Understanding the intricate steps involved in Rutin production unveils the meticulous craftsmanship employed by HimPharm. Each stage contributes to the purity and efficacy of the final product.

Step 1: Raw Material Preparation: HimPharm initiates the process by selecting premium-quality Sophora japonica, ensuring that the botanical sources are at their peak potency.

Step 2: Extraction: The selected raw materials undergo a sophisticated extraction process. HimPharm employs advanced extraction techniques to isolate Rutin efficiently, maintaining its therapeutic properties.

Step 3: Purification: Post-extraction, Rutin undergoes purification, a crucial step to eliminate impurities and achieve the desired level of purity. HimPharm’s commitment to high standards ensures a purified Rutin extract.

Step 4: Concentration: The purified extract then undergoes concentration, enhancing the potency of Rutin. This step is pivotal in ensuring that the final product possesses optimal therapeutic effects.

Step 5: Formulation: Rutin, in its concentrated form, is skillfully formulated into various pharmaceutical forms, adapting to the diverse needs of the healthcare and natural product industries.

Step 6: Quality Control Testing: Rigorous quality control testing is integrated throughout the manufacturing process. HimPharm’s dedication to quality assurance is evident in the comprehensive testing protocols applied to assess the purity, potency, and safety of Rutin.

Step 7: Packaging and Distribution: Upon successful quality control assessments, the final Rutin product undergoes meticulous packaging and labeling processes before being distributed globally. HimPharm ensures that the journey from production to consumption maintains the integrity of Rutin.

Testing in Rutin Manufacturing

Quality control is a cornerstone of HimPharm’s Rutin manufacturing process. The testing procedures adopted by HimPharm serve as a stringent filter, ensuring that each batch meets the highest standards.

  • Identity Testing: Through macroscopic and microscopic examinations, the authenticity and botanical identity of Rutin’s raw material are verified.
  • Purity Analysis: Chemical analysis is employed to assess the purity of the Rutin extract, guaranteeing minimal impurities and contaminants.
  • Potency Assay: Determining the concentration of active compounds, particularly Rutin, ensures consistent therapeutic efficacy across batches.
  • Microbiological Testing: To maintain product safety, Rutin undergoes screening for microbial contaminants, aligning with regulatory standards.
  • Stability Testing: The final product’s stability is evaluated under various storage conditions, ensuring a reliable shelf-life and sustained product integrity.

Navigating Production Bottlenecks in Rutin Manufacturing

The pharmaceutical landscape is dynamic, presenting inherent challenges. HimPharm addresses these challenges proactively, ensuring that Rutin production remains a seamless process.

  • Raw Material Sourcing: A consistent and reliable supply of high-quality raw materials is ensured, mitigating potential disruptions in manufacturing operations.
  • Process Optimization: HimPharm continually streamlines manufacturing processes, enhancing efficiency without compromising product quality.
  • Regulatory Compliance: Navigating complex regulatory requirements is paramount. HimPharm remains steadfast in adhering to international quality standards and Good Manufacturing Practices (GMP).
  • Supply Chain Logistics: Efficient management of logistics and distribution channels minimizes lead times, ensuring timely delivery of Rutin to global clients.

HimPharm’s proactive approach to addressing production bottlenecks underscores its commitment to delivering Rutin of the highest quality and efficacy. By strategically planning and optimizing manufacturing processes, HimPharm ensures uninterrupted workflow and timely delivery, meeting the evolving demands of the pharmaceutical and natural product industries.

HimPharm’s Manufacturing Advantage: Rutin Production

HimPharm is the leading bulk Rutin supplier for the pharmaceutical and healthcare industry. HimPharm’s manufacturing advantage lies in its unwavering commitment to excellence and innovation. With a legacy spanning over four decades, HimPharm has established itself as a pioneer in Rutin API production, setting benchmarks for quality and reliability.

  • Cutting-edge Technologies: HimPharm leverages cutting-edge technologies to optimize Rutin production processes. Advanced extraction and purification techniques ensure the purity and potency of Rutin extracts.
  • State-of-the-Art Facilities: Equipped with state-of-the-art facilities, HimPharm maintains the highest standards of manufacturing. From raw material handling to formulation and packaging, every aspect of Rutin production adheres to stringent quality control measures.
  • Scalable Production Capacity: HimPharm’s modern manufacturing facilities are designed to scale production seamlessly, accommodating varying demand volumes. Whether catering to small-scale orders or large-scale bulk requirements, HimPharm ensures consistent quality and on-time delivery.
  • Quality Assurance: HimPharm’s commitment to quality assurance is unwavering. A dedicated team of experts oversees every stage of Rutin production, ensuring compliance with international regulatory standards and customer specifications.
  • Flexibility and Customization: HimPharm offers flexibility and customization options to meet diverse customer needs. From tailored formulations to specialized packaging, HimPharm collaborates closely with clients to deliver Rutin solutions that align with their unique requirements.
  • Continuous Improvement: HimPharm fosters a culture of continuous improvement and innovation. Through ongoing research and development initiatives, HimPharm remains at the forefront of Rutin production, exploring new technologies and optimizing processes to enhance product quality and efficiency.

HimPharm’s manufacturing advantage extends beyond Rutin production, reflecting its commitment to excellence and customer satisfaction. By prioritizing quality, innovation, and customer-centricity, HimPharm continues to redefine industry standards and drive progress in the pharmaceutical and natural product sectors.


Recap of Key Insights

In conclusion, Rutin stands as a remarkable phytochemical with diverse therapeutic properties and applications. From its role in cardiovascular health to its anti-inflammatory and antioxidant benefits, Rutin continues to garner attention in the pharmaceutical and natural product industries.

Leveraging HimPharm’s Commitment to Quality

Partnering with HimPharm for Rutin sourcing ensures access to premium-quality products manufactured with precision and expertise. HimPharm’s unparalleled manufacturing standards, commitment to innovation, and customer-centric approach make it the preferred choice for Rutin and other phytochemical needs.

Empowering Your Journey in Healthcare and Natural Products

As you embark on your journey in the healthcare and natural product industries, HimPharm stands as a trusted ally, offering comprehensive solutions and unparalleled expertise. With HimPharm by your side, you can unlock new possibilities, drive innovation, and transform healthcare outcomes for communities worldwide.

In closing, HimPharm invites you to explore the vast potential of Rutin and other phytochemicals, leveraging its expertise and manufacturing capabilities to realize your vision and make a lasting impact in the world of healthcare and natural products.

Write to or Call HimPharm to Request a Quote, COA, and MSDS.


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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.


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