Trioxsalen USP – API used in skin preperations
Trioxsalen USP is an API which is used by the Pharma industry.
CAS Number : 3902-71-4
Molecular formula: C14H12O3
Trioxsalen USP (trimethylpsoralen, trioxysalen or trisoralen) is a furanocoumarin and a psoralen derivative. It is obtained from several plants, mainly Psoralea corylifolia. Like other psoralens it causes photosensitization of the skin. It is administered either topically or orally in conjunction with UV-A (the least damaging form of ultraviolet light) for phototherapy treatment of vitiligo and hand eczema. After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death unless repaired by cellular mechanisms.
At Himachal Pharmaceuticals we manufacture Trioxsalen USP as per United States Pharmacopoeia standards . It is only available for bulk requirements as Active Pharmaceutical Ingredients for the Pharmaceutical or Drug manufacturing companies, agents or other industrial bulk consumers.