Calcium Sennoside

Sennoside A
Sennoside B
Calcium Sennoside USP and IP grade

Written by

Reviewed by

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Gaurav Sood

Partner - HimPharm

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Dr B M Sood

Chairman - HimPharm

Calcium Sennoside by HimPharm- Guide for Pharmaceutical and Healthcare Industries

CAS Number: 81-27-6 (Sennoside A) , 128-57-4 (Sennoside B), 517-43-1 ,  52730-37-7 (Calcium Salt)

Molecular Formula: C42H36CaO20

Calcium Sennoside is a vital Active Pharmaceutical Ingredient (API) used by the pharmaceutical industry, particularly in the production of drugs aimed at addressing constipation. Derived from senna leaves, Calcium Sennoside undergoes meticulous manufacturing processes to meet the standards set by Indian Pharmacopoeia (IP) and United States Pharmacopeia (USP).

Calcium Sennoside holds a crucial place in the pharmaceutical, drug, and natural products industry. Its role as a natural laxative makes it sought after by pharmaceutical companies aiming to formulate effective medications for short-term constipation treatment. The natural origin of Calcium Sennoside aligns with the growing trend in the healthcare sector towards herbal medicine, nutraceuticals, and plant-based pharmaceuticals.

Overview

Calcium Sennoside

Calcium Sennoside is available in various forms, each with distinct characteristics. The IP and USP standards ensure that the quality and efficacy meet the required benchmarks. Sennoside A and Sennoside B are specific dimeric glycosides derived from the genus Senna, known for their laxative properties.

Calcium Sennoside is primarily used in the pharmaceutical industry for the short-term treatment of constipation. Its application extends to drug manufacturing, where it serves as a key ingredient in formulations designed to alleviate constipation symptoms.

In its various forms, Calcium Sennoside appears as a fine powder or granules, depending on the manufacturing and processing methods employed.

Senna leaves, the natural source of Calcium Sennoside, undergo extraction processes to isolate the beneficial compounds. These processes are meticulously executed to ensure the purity and potency of the final product.

The importance of Calcium Sennoside lies in its natural origin and efficacy as a laxative. As the pharmaceutical industry embraces herbal and plant-based alternatives, Calcium Sennoside becomes a valuable component in formulating medicines for constipation relief.

Calcium Sennoside finds extensive use in the formulation of pharmaceutical products, particularly those designed for short-term constipation treatment. Its inclusion in drug manufacturing reflects the industry’s commitment to providing effective and natural solutions to common health issues.

Senna Glycosides and Laxative Properties

Senna Glycosides, including Sennoside A and Sennoside B, are anthraquinone derivatives with potent laxative properties. These compounds are named after their abundant occurrence in plants of the genus Senna.

The natural laxative properties of Senna Glycosides make them a preferred choice in the pharmaceutical industry for addressing constipation. The mechanism involves stimulating bowel movements, providing relief to individuals experiencing short-term constipation.

Calcium Sennoside, as a key component of Senna Glycosides, is employed for the short-term treatment of constipation. Its efficacy in promoting bowel regularity positions it as a valuable medicinal solution for individuals seeking immediate relief from constipation symptoms.

Genus Senna: Natural Source of Sennosides

Genus Senna comprises plants known for their medicinal properties, particularly in addressing gastrointestinal issues. Senna plants are rich sources of Sennosides, making them valuable in pharmaceutical applications.

Sennosides abundantly occur in various parts of Senna plants, with leaves being the primary source. The extraction of Sennosides from these plants involves careful processes to harness their medicinal benefits.

The extraction of Sennosides involves obtaining the beneficial compounds from Senna leaves. This extraction is carried out using methods that maintain the integrity and potency of the Sennosides.

HimPharm Manufacturing Standards

HimPharm, a reputable player in the pharmaceutical manufacturing industry since 1979, specializes in the production of Calcium Sennoside. With over a century of experience in herbs and herbal products, HimPharm has established itself as a reliable source for high-quality plant-based APIs.

One of the distinguishing factors of HimPharm’s manufacturing process is its strict adherence to Indian Pharmacopoeia (IP) and United States Pharmacopeia (USP) standards. This commitment ensures that the Calcium Sennoside produced meets the stringent quality benchmarks set by the industry.

HimPharm offers Calcium Sennoside in bulk, catering to the needs of pharmaceutical companies, drug manufacturers, and other industrial bulk consumers. This availability in large quantities ensures a stable supply for those seeking Calcium Sennoside as an active ingredient.

Calcium Sennoside Production Processes

Senna-Cassia-angustifolia-plant

The production of Calcium Sennoside at HimPharm involves a carefully outlined manufacturing process. From the sourcing of raw materials to the final product, each step is meticulously executed to maintain the quality and purity of the API.

  • Sourcing and Sorting Senna Leaves
  • Cleaning
  • Drying
  • Size Reduction
  • Solvent Extraction
  • Filtration
  • Concentration
  • Precipitation
  • Drying of Calcium Sennoside
  • Final Quality Control and Testing
  • Packaging

This step-by-step manufacturing process ensures the production of high-quality Calcium Sennoside, meeting the stringent standards set by Indian Pharmacopoeia (IP) and United States Pharmacopeia (USP).

Quality assurance is vital in HimPharm’s manufacturing process. Rigorous testing protocols are implemented to verify the potency, purity, and safety of Calcium Sennoside. This commitment to quality ensures that the final product meets or exceeds industry standards.

To address potential bottlenecks in production, HimPharm leverages its modern facility, equipped to scale manufacturing from small to large batches. This flexibility allows the company to meet varying demands in the market, providing a reliable and efficient supply chain.

HimPharm’s manufacturing facility is a testament to its commitment to quality and innovation. With state-of-the-art equipment and a skilled workforce, HimPharm stands as a reliable partner for pharmaceutical companies seeking top-quality plant-based APIs.

Conclusion

In conclusion, Calcium Sennoside plays a crucial role in the pharmaceutical and healthcare industries, particularly in the formulation of medicines for constipation relief. HimPharm’s commitment to quality, adherence to industry standards, and the availability of Calcium Sennoside in bulk positions it as a preferred supplier for pharmaceutical companies, drug manufacturers, and industrial bulk consumers. As the demand for natural and plant-based solutions in healthcare grows, HimPharm stands ready to meet the evolving needs of the industry.

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These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

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