In the ever-evolving landscape of healthcare, the pursuit of holistic and natural solutions has gained significant momentum. As a response to this growing demand, HimPharm stands at the forefront of innovation, specializing in the production of Phytochemicals, Alkaloids, and Active Pharmaceutical Ingredients (APIs) sourced from plants. Below we will look into the vast world of plant-based medicine, exploring the significance of Phytochemicals, the role of Alkaloids in medicinal plants, and the advantages of sourcing APIs from plant origins.
Alkaloids, a class of naturally occurring organic compounds, exhibit diverse pharmacological effects. Found in medicinal plants, Alkaloids play a crucial role in plant defense mechanisms. HimPharm recognizes the potency of Alkaloids and harnesses their therapeutic potential through innovative extraction processes.
Examples of Plants Rich in Alkaloids: Plants like the Cinchona tree, known for quinine highlights the rich diversity of Alkaloids in nature. HimPharm’s commitment to sustainable and ethical practices ensures the responsible sourcing of these plant-based treasures.
APIs are the cornerstone of pharmaceutical formulations. Obtained from plant sources, these plant based ingredients serve as the active components in various medicines. HimPharm’s dedication to sustainable manufacturing practices emphasizes the importance of utilizing plant-derived APIs for enhanced therapeutic outcomes.
The advantages of sourcing APIs from plants are multifaceted. From a sustainability perspective, plant-derived APIs contribute to environmentally friendly practices. Additionally, the holistic nature of plant-based compounds often results in fewer side effects compared to their synthetic counterparts.
HimPharm’s manufacturing process integrates cutting-edge technology with a profound respect for nature. Through meticulous extraction and purification methods, the company ensures the preservation of the plant’s bioactive compounds, delivering products of unparalleled quality.
In a world increasingly conscious of environmental impact, HimPharm takes pride in its commitment to sustainability. The company employs ethical sourcing practices, minimizing its ecological footprint while contributing to the welfare of local communities.
HimPharm specializes in isolation of active principles from natural sources, through semi-synthesis. This results in the production of Phytochemicals which are the building blocks of many products. These Alkaloids or APIs are then sold to companies who either combine them with other ingredients or further process them to make allopathic products that you see on shelves at pharmacies and drug stores.
10 DAB III, or 10-Deacetyl Baccatin III is important in the synthesis of anti-cancer drugs, like Paclitaxel and Docitaxel. Derived from the Taxus baccata tree, 10 DAB III emerges as a sustainable alternative to the environmentally impactful extraction methods previously employed in obtaining Paclitaxel from Yew trees.
16-Dehydropregnenolone Acetate, commonly known as 16 DPA, is a key compound with significant implications in the pharmaceutical industry. It is a chemical entity that serves as a crucial intermediate in the synthesis of various steroids and sex hormones
Berberine, a natural alkaloid, is sourced from various plants. This compound has gained recognition for its multiple applications. HimPharm manufactures all three varieties of Berberine – Hydrochloride (HCL),
Sulphate and Tannate.
Bergapten is an Intermediate API, used in medicinal formulations. Derived from bergamot and various citrus essential oils, Bergapten, scientifically known as 5-methoxypsoralen, has multiple uses ranging from treating psoriasis to promoting tanning in suntan lotion.
Derived from Senna leaves Calcium Sennoside is a vital Active Pharmaceutical Ingredient (API) used by the pharmaceutical industry, particularly in the production of drugs aimed at addressing constipation.
Camptothecin (CPT) is a cytotoxic quinoline alkaloid. Known for its role in inhibiting topoisomerase I (topo I), this natural compound is primarily used as an intermediate in the development of cancer treatment derivatives like Topotecan and Irinotecan.
Chrysarobin is a pale orange-yellow powder that has many different therapeutic benefits. Chrysarobin is a powerful stimulant for skin health. It has Antiseptic, Anti-Parasitic properties and is a Powerful Skin Irritant. It is used in wound care, skin infections and traditionally to treat psoriasis and fungal infections.
Colchicine is a chemical compound which is extracted from the roots in the plants of the genus Colchicum, specifically the Autumn crocus. Initially utilized for treating rheumatic complaints, especially gout. It is now also utilised in Familial Mediterranean Fever (FMF) and as Pericarditis treatment. Its anti-inflammatory properties contribute to its therapeutic use in herbal formulations targeting various health concerns.
Curcumin, is a bioactive compound derived from the turmeric plant (Curcuma longa). It is known for potent medicinal properties including anti-inflammatory, antioxidant, and antimicrobial properties. Curcumin finds application across multiple industries, including pharmaceuticals, food and beverage, cosmetics, and dietary supplements.
Diosgenin, Crude Diosgenin also called Wild Yam Extract is a naturally occurring steroid obtained from certain plant sources, primarily Dioscorea species. It serves as a crucial precursor for corticosteroids and various sex hormones, contributing to the synthesis of essential compounds such as DHA, progesterone and prednisolone.The primary natural source of Diosgenin is certain species of Dioscorea, commonly known as wild yam or Chinese yam.
Hypericum perforatum extract, commonly known as St John’s wort, is derived from the plant Hypericum perforatum. It is renowned for its diverse range of active constituents, notably hypericin and hyperforin. These compounds contribute to the extract’s therapeutic properties, making it a valuable resource in various applications. It has generated a lot of attention for its potential as an antidepressant. It may also be used for alcoholism management and its anti-bacterial properties
Methoxsalen, is a crucial medication employed in the treatment of various skin conditions, including psoriasis, eczema, vitiligo, and certain cutaneous lymphomas. It operates synergistically with ultraviolet (UVA) light. Methoxsalen belongs to a class of organic natural molecules known as furanocoumarins and is isolated from the plant Ammi majus.
Paclitaxel, a powerful chemotherapy agent, belongs to a class of medications known as plant alkaloids. Derived from the needles of the Taxus tree, Paclitaxel has revolutionized cancer treatment since its discovery. Paclitaxel finds extensive applications in the treatment of various cancers, including ovarian, breast, lung, and cervical cancers, among others. Its efficacy extends to Kaposi’s sarcoma and leukemia, making it a versatile chemotherapy agent.
Podophyllum Resin USP, also called Podophyllum Peltatum USP is derived from Podophyllum Peltatum plant commonly known as Mayapple. It is a vital natural resource serving as the starting material for the semi-synthesis of anti-cancer drugs such as etoposide, teniposide, and etopophos. Derived from the North American variety of Podophyllum, this compound has played a pivotal role in the treatment of lung and testicular cancers, as well as certain leukemias.
Podophyllum Resin BP, also called Podophyllin Hexandrum and Podophyllin Emodi is a potent medicinal substance derived from the rhizome of the Himalayan Mayapple plant (Podophyllum hexandrum). Podophyllin Hexandrum holds significant therapeutic value. Its purgative properties helps addressing severe cases of constipation and intestinal worms. Its role in dermatology and oncology underscores its diverse applications in modern medicine.
Podophyllum Toxin USP, a non-alkaloid toxin lignin, is a key component derived from the roots and rhizomes of Podophyllum species. Podophyllin is renowned for its pharmacological significance. This toxin plays a vital role in the treatment of various medical conditions, particularly in dermatology and oncology. Its primary use lies in the treatment of skin conditions, notably genital warts and molluscum contagiosum. It also serves as a precursor for the synthesis of etoposide, a potent anti-cancer drug used in chemotherapy regimens.
Psoralene, or Psoralen is the foundational compound in the family of natural products termed furocoumarins. Psoralene holds significant therapeutic potential, particularly in dermatological treatments and phototherapy. Its high UV absorbance capacity makes it indispensable in treatments targeting skin disorders like psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma. It is incorporated into PUVA (Psoralen + UVA) therapy for the management of various skin conditions.
Quercetin Dihydrate is the dihydrate preparation of Quercetin. Renowned for its therapeutic properties, Quercetin Dihydrate has garnered attention as a potent flavonoid with many health benefits. Found abundantly in various plant-based foods and supplements. Its antioxidant properties may improve immune system and combat free radical damage. Its anti-inflammatory effects have positioned it as a promising adjunct therapy for various inflammatory conditions, ranging from arthritis to respiratory ailments.
Quinine is a natural alkaloid renowned for its multiple properties, encompassing antipyretic, antimalarial, analgesic, and anti-inflammatory attributes, alongside its distinct bitter taste. Originating from the bark of the cinchona tree, it holds a pivotal place in medicinal history, particularly in combating malaria. Quinine’s discovery dates back to 1820, marking a pivotal milestone in the therapeutic landscape, as it became the first chemical compound utilized to treat an infectious disease.
Reserpine is an indole alkaloid renowned for its dual therapeutic roles as an antipsychotic & antihypertensive drug. It has been utilised in managing high blood pressure and alleviating psychotic behaviours. Its efficacy in controlling hypertension, particularly when used in combination with thiazide diuretics or vasodilators, has significantly enhanced treatment options for patients with high blood pressure. Beyond its therapeutic applications, Reserpine has also been utilised in veterinary medicine as a long-acting tranquiliser.
Rutin, also known as rutoside, quercetin-3-rutinoside, or sophorin, stands as a prominent citrus flavonoid glycoside. Rutin’s uses span a spectrum of health applications, from its role in mitigating inflammation to its potential in cardiovascular health, Rutin’s versatility extends across multiple domains. Rutin’s antioxidant properties make it a formidable combatant against oxidative stress, a contributor to various chronic diseases. Its anti-inflammatory effects position it as a potential ally in addressing conditions marked by excessive inflammation. Rutin exhibits antithrombotic properties, contributing to cardiovascular health.
Santonin, an alkaloid or phytochemical, has been recognized for its anthelmintic properties. This organic compound is utilized in expelling parasitic worms, notably Ascaris lumbricoides, from the human body. Historically, Santonin was a crucial component in anthelmintic treatments, offering a means to combat roundworm infestations and threadworm parasitosis effectively. Additionally, Santonin is instrumental in addressing various ascarid parasitoses, including threadworm parasitosis, reflecting its broad spectrum of anthelmintic activity.
Silymarin represents a standardized extract derived from the seeds of the milk thistle plant (Silybum marianum). This comprises flavonolignans, including silibinin A and B, isosilibinin A and B, silicristin, and silidianin. Renowned for its benefits in liver health, Silymarin has diverse therapeutic properties & applications. Silymarin finds extensive use in the treatment of liver diseases, including chronic liver disease, liver cirrhosis, and hepatitis. Its hepatoprotective, antioxidant, and anti-inflammatory properties make it a valuable asset in combating oxidative stress, promoting liver regeneration, and mitigating the progression of liver disorders.